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Spina bifida is caused by incomplete closure of the embryonic neural tube in the forst month of pregnancy. It is one of a range of neural tube defects.
Taking folic acid supplements halps to prevent these complications.

It is usually thought of as environmental, rather than genetic: some medications, as well as other situations like fever on the part of the mother, are linked with neural tube defects.
However - it has been observed that a mother who has a child with spina bifida has an elevated chance of having a second child also with spina bifida, suggesting a genetic predisposition. The nature of this disposition is not yet known, but it is most likely to be polygenic - controlled by a complex interaction of multiple different genes.

2007-12-09 22:44:29 · answer #1 · answered by gribbling 7 · 0 0

There is more than one form of spina bifida. I do not believe they are primarily hereditary in origin, but rather, have an environmental etiology.

There has been a major decline in the incidence of spina bifida in the U.S. after the introduction of food fortification with folic acid (a B-vitamin) in the 1990s. (1)

2007-12-09 15:36:15 · answer #2 · answered by Doctor J 7 · 2 0

on your occasion you have 2 alleles T and t that are variations of an identical gene. T is dominant because of the fact that is written as a capital and t is recessive because of the fact that is written decrease case. once you pass 2 TT persons you oftentimes get all TT offspring because of the fact the mothers and fathers can in basic terms pass on T alleles, an identical with tt. although once you pass Tt x Tt, you get a mix of genotypes, the Tt offspring have a duplicate of the two alleles. in case you have been observing the phenotypes of those offspring i.e. the way they appeared, you may locate that Tt persons have been indistinguishable from TT, because of the fact the T allele is dominant and mask the presence of the recessive t allele. An occasion: T is the allele for tall plant life in Mendel's pea plant experiments and t is short plant life. once you do a Tt x Tt pass, you get 3 tall plant life for each short a million, it is via the fact TT and 2Tt are tall and in basic terms tt is short. Autosomal refers to inheritance varieties for genes which at the instant are not on the X chromosome (animals in basic terms). X-correct inheritance has a diverse development which i'm effective you will study quickly.

2016-12-17 13:04:22 · answer #3 · answered by Anonymous · 0 0

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