Try answering this challenging question?!!?

Question

Do mistakes happen during translation? What could be the consequences of mistakes? Are there any mechanisms in place to avoid this?

Plz provide me with a brief explanation. Best nswer will get 10 points.

Answer 1

Yes, mistakes happen during translation, consequences of the mistakes could be diseases or there could be none depending on what kind of mistake is made such as a substitution, insertion, or deletion. when an base is changed it is called a point mutation. If the 3rd codon is substituted most of the time it will not affect any thing, if any thing else is changed chances are it will change the outcome of the amino acid. Insertion and deletion mess up the whole polypeptide chain so everything goes wrong in those cases, it is called a frameshift mutation. The mechegnism to avoid this is RNA Polymerase, it "proofreads" the RNA for errors and corrects them if there are errors.

Answer 2

Yes, mistakes will always happen in translation. Mechanisms in place to catch mistakes are multiple translations and comparison by more than one individual.
Even then some mistakes will still be made, but far fewer.

If you were a little more specific in what was being translated I could have given a more extensive answer.

Answer 3

They do, but to a lesser extent and they don't lead to such big problems as DNA mutations as the "mistakes" are not transmitted to the progeny (they are not incorporated in the genetic material, as they happen in somatic cells). Moreover, the frequency is so low that even if some of the mRNA is translated wrongly, the great majority of the protein will still result wild-type, so the function is not lost (unless the mutant protein is a dominant negative). There are mechanisms which detect and eliminate aberrant mRNAs, which mainly work through microRNAs (miRNA), the function of which is that of rendering the aberrant mRNA very unstable - the life becomes so short that only a small proportion of the protein becomes mutant.

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Answer 4

Mistakes can happen everywhere. However yes they do occur during translation, I think you are refering to DNA here, so If you have say ACGGT it should be translated to TCGGA however if something is missing and it gets translated as TCGA, it is called a deletion, and can result in a deformity, something in the body not working, or nothing. It is relative to what the mistake happens on, and what it codes for. There are really not to many thinks to stop this since it is a natural occuance.

Answer 5

Sure mistakes happen in translation. I think this is an example you will understand: The bible has been translated lots of times into lots of different languages by lots of different religions. Wouldn't that be why there are so many disagreements among the various religions?

But, if you really meant this to be under the biology questions, I will let the other anwerers speak for me.

Answer 6

Mistakes are inherent in translation....to avoid these mistakes it pays to have the translation done by more than one translator independently and like mathmatical calculations it also pays to retranslate back again to check for misinterpretations.Dependant on the field worked in,then the concequences could be dire.So in effect it is well worth paying the piper to sing the tune in key...or in the case of translation to have more than one piper !...my mistake i translated your question as language translation,not as DNA.