How does denaturation affect sedimentation of macromolecules?

Answer 1

It can change the way it reacts with Stokes Law, by changing the charge and solubility of the particles. The particles will then drop out of solution at different rates if the protein structure is altered.

Answer 2

Haha Jess. A good way to solve your lab exercises! I was hesitant to try this system at first because I thought no one would really answer. I see that someone has answered the question for you already. Okay, time to write the answer on my lab manual. Hehe. Good luck with the rest of the manual. The questions are really difficult!