Mutation that deletes or adds on DNA nucleotide..need answer ASAP!!!?

Question

Mutation that deletes or adds on DNA nucleotide..need answer ASAP!!!?
A mutation that deletes or adds one DNA nucleotide is much more serious than on that substitutes or replaces one nucleotide with another. Why is this?

Answer 1

Here's a though exercise for you:
Imagine your shirt that has 7 buttons and 7 buttonholes. Everyday you start at the bottom and button up your shirt. Everything fits and your shirt goes on normally. OK, so one night the mutation fairy comes into your closet and adds a button. You get up and button up your shirt starting at the bottom, but by the time you get to the top, there is an extra button and your shirt is all messed up.

If you haven't figured it out by now, the buttons and buttonholes are individual nucletide pairs (octets actually). Adding one effects the whole chain. Simply changing one nucleotide pair for another would be like making one of the 7 white buttons orange. The whole shirt can still be buttoned up properly, but it just looks wierd.

Hope this helps.

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Answer 2

The genetic code is study in triplicate (codons) while piecing jointly amino acids right into a protein. while there is an insertion or deletion of nucleotides otherwise widely used as a frameshift mutation, a shift interior the examining of those codons happens. this might effect in the two too many, too little, or the incorrect amino acids preferable to an inactive protein. A substitution of nucleotides (missense mutation) won't be as undesirable because of the fact a unmarried amino acid might properly be laid out in ability of extra suitable than one codon. So a substitution can nevertheless effect in a functional protein.

Answer 3

You should do your own homework
:-)