HELP.What can be the background behind my science project! ITS DUE TOMMORROW!?

Question

My partner and i timed how long alieve (the medicine) takes to dissolve in different liquids with different phs, but are project needs relevance and it doesnt make since with reation rate. This project makes since with solubiliy as my teacher told me but I DONT KNOW HOW.!PLEEASE HELP!

Answer 1

Dr. Dave P is wrong. Aleve is naproxen sodium (with cornstarch binding) which is clearly not ibuprofen.

You are probably measuring the dissolution rate of the cornstarch and not the acutal medicine.

Relevance could be in vitro because the stomach is an acidic environment.

good luck!

Answer 2

The relevance is that in its physical form the medecine is useless, it needs to dissolve so the body can absorb it - that's the basics and is also why you get drugs directly into your blood stream in hospital - it's faster.

But! You may not want a drug to dissolve in your stomach as the stomach is ph is very low (acidic) and the drugs could be destroyed in those conditions. Most drugs and nutrients are absorbed in the small intestine which has a much more neutral ph. So to stop your drug being destroyed in the stomach you make sure it doesn't dissolve in acid ph, but does in a more neutral ph.

Make sure I get a credit on the science project!

Answer 3

Your body will be able to absorb a medication in liquid form much quicker than one it has to break down. If you have a liquid that can dissolve your medication quicker then it can work quicker in your body. Thats why Alka Seltzer became so popular...plop plop fizz fizz

Answer 4

Aleve is basically ibuprofen and cornstarch binder.

It is a carboxylic acid.

It should dissolve fast as you raise the pH - is that what your experimental data shows?

ibuprofen:

ref: http://en.wikipedia.org/wiki/Ibuprofen