from Which website can I get a complete literature of the drug Combizar? my mom wants a printout now...?

Question

I cant seem to find the complete literature for Combizar online...please help!

Answer 1

Your pharmacist can give you the literature enclosed with Combizar. It's a diuretic. Thereapharma makes it and here is what they have to say online:


Combizar
Losartan + Hydrochlorothiazide

Formulation:
Each tablet contains:
50 mg Losartan potassium
12.5 mg Hydrochlorothiazide (HCTZ)
or
100 mg Losartan potassium
25 mg Hydrochlorothiazide

Indications:
Treatment of hypertension; for patients in whom combination therapy is appropriate

Dosage and Administration:
Usual Initial and Maintenance Adult Dose: 1 tablet of Losartan 50mg + HCTZ 12.5mg FDC once daily.
For patients who do not respond adequately, adjust to a maximum dose of: 1 tablet of Losartan 100 mg + HCTZ 25 mg FDC daily or, 2 tablets of Losartan 50 mg + HCTZ 12.5 mg FDC daily
In general, the antihypertensive effect is attained within 3 weeks after initiation of therapy.

Contraindications:
Hypersensitivity to any component of the product
Hypersensitivity to sulfonamide-derived drugs
Pregnancy
Patients with anuria

Precautions:
- Do not initiate use of losartan-HCTZ FDC in patients who are intravascularly volume-depleted (e.g., those treated with high-dose diuretics).
- Losartan-HCTZ FDC is not recommended for patients with severe renal impairment (creatinine clearance < 30 mL/min) or patients with hepatic impairment.
- Based on pharmacokinetic data demonstrating significantly increased plasma concentrations of losartan in cirrhotic patients, a lower dose should be considered for patients with a history of hepatic impairment. Hence, losartan-HCTZ FDC is not recommended for patients who require dose titration with losartan.
- Losartan may increase blood urea and serum creatinine in patients with bilateral renal artery stenosis or stenosis of the artery to a solitary kidney. These changes in renal function may be reversible upon discontinuation of therapy.
- Use in Nursing Women: It is not known whether losartan is excreted in human milk. HCTZ appears in human milk. Because of the potential for adverse effects on the nursing infant, a decision should be made to discontinue nursing or discontinue the drug, taking into account the importance of the drug to the mother.

Answer 2

Try webmd.com