Is it possible to track the movements of bacteria within a large living animal?

Question

For an enteric bacterium, would it be possible to track the movements of the bacterium within the living host, without detrimental effects to the host?

This has been done with mice and Salmonella before: does anyone have a reference for this?

Could you label the bacteria with something that could be tracked through the host?

Answer 1

The experiment you are talking about with the salmonella was done using lux, an enzyme which produces luminescence.

Genes for lux or luc are inserted into plasmids which are then transferred into the bacterium.

See references below.

(BTW, try using google scholar advanced search for this kind of thing, its tops)

Answer 2

I would guess some sort of radio-active chemical marker would do the trick..

Answer 3

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