Is it better to ink cartoons with the pencil or brush stroke when using the pen tool?

Answer 1

It obviously depends on the style you wish to impart to the image. If you want a hard edged line, you use a hard edged brush. You want a softer line, you select a softer edge. If you want a scratch pencil effect, you use THAT tool.

I have seen plenty of animations where artists have used these tools, and others.

There is no "better." That's why applications such as Photoshop have such a selection. It is for the artist to decide.

Answer 2

Leading 3D Animation Software : http://3dAnimationCartoons.com/?qtpk