What is inital step in DNA replication?

Question

a- breakdown of the unclear envelope
b- formation of the mitiotic spindle
c- formation of the cleavage furrow
d- attachment of the chromosome to the plasma membrane
e- unwinding of the DNA double helix

Answer 1

I would say the very first step is obtaining the DNA material. This DNA might be extracted from old bones, amber or even living tissue.
Another so called first step would be removing as much of the foreign material as possible.
One last first step would be placing the DNA in a growing medium in a suitable container. I did PCR replication and its really quite simple.
Sorry for all the first steps but hopefully one of them is what you were looking for

Answer 2

DNA unwinds and is "unzipped" down the middle - between the pairs of nitrogen bases.