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You are working on a team that is designing a new drug. In order for this drug to work, it must enter the cytoplasm of specific target cells. Which of the following would not be a factor that determines whether the molecule enters the cell?

A) size of the drug molecule
B) polarity of the drug molecule
C) charge on the drug molecule
D) similarity of the drug molecule to other molecules transported by the target cells
E) lipid composition of the target cells' plasma membrane

and can u pls justify ur answer

2007-10-18 15:59:49 · 5 answers · asked by martha jones 1 in Science & Mathematics Biology

5 answers

The answer is E. The lipid composition of different cell types is quite similar. Different lipids have similar properties. A fat soluble chemical can go through the lipid layer of the cell membrane easily, and the lipid composition is no concern. A charged or very polar molecule may have to enter through aqueous channel in the protein molecules, which may be unique in different cell types.

2007-10-18 18:07:19 · answer #1 · answered by OKIM IM 7 · 0 4

I would say E. but that's just my opinion. Most cell plasma membranes are composed of a vast majority of phospholipids so I doubt it would vary enough to matter. The drug would have to cross by active or passive transport which all of the rest would probably effect

2007-10-18 16:19:10 · answer #2 · answered by burnholywater 2 · 0 3

the answer is E. the drug is NOT entering through the membrane which means that it can be recognized by a receptor or transported through a pump. the lipid composition is irrelevant.

2007-10-18 16:23:34 · answer #3 · answered by Tachycardia22 1 · 0 3

nicely, effective lots of the cellular membraine is the phospholipid bilayer, yet to be certain that extensive or surprisingly polar molecules to pass into the cellular, there are additionally channels that are upregulated and activated in distinct approaches. The Na/ok ATPase facilitates the energetic transport of Sodium and Potassium out and in of the cellular to maintain the proper tonicity.

2017-01-03 21:40:10 · answer #4 · answered by Anonymous · 0 0

The answer is actually D. I looked it up in a college level Bio 101 book. Please do research before giving wrong answers! :)

2015-09-25 06:20:43 · answer #5 · answered by Travis 1 · 6 0

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