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Such disorders are red-green color blindness, hemophilia, and muscular dystrophy. Why are they more common in males?

2007-10-18 13:33:41 · 5 answers · asked by celestial_yellow_munky 1 in Science & Mathematics Biology

5 answers

No, Y-linked disorders exist. The chromosome is very small so it has fewer genes and fewer disorders. SRY (sex determining Y) is the main male character determinant. If this gene is mutated the individual will appear female despite being XY
http://www.gender.org.uk/about/04embryo/41_xychm.htm

Without two copies possible there is no dominance or recessiveness unless it occurred in a XYY individual. Then the incomplete SRY gene would be recessive to the other Y's functional copy.

The MSY, for 'male-specific region of the Y, is 23Mb. About 10–15% of the MSY moved there from the X chromosome 'recently' and contains 2 genes.
Another 20% of the MSY consists of more distantly related X chromosome sequence. The remaining 15Mb contains other male specific genes and a novel scattered 5.4Mb of palindromic DNA that aids in editing Y repairing errors in sequence.
http://www.nature.com/nature/journal/v423/n6942/full/423810a.html

2007-10-18 13:59:06 · answer #1 · answered by gardengallivant 7 · 0 0

actually genetic disorder usually require both parents to have the genes. so that doesn't necessarily mean that it has to be just on the x chromosome. it could be the y chromosome.

but the reason why it's more common in men is because with girls they have two x's. meaning that because one gene is defective there's always the other x. where as guys only have one x to depend on.

there was an article in the new york times talking about genetics i think it's title went somewhere along the lines of "mama's boy" but basically the men's y has been made to just reproduce and they contain about...50 genes or something like that. whereas the x chromosome does all the work. literally. it contains over 1500 genes (something like that) and carries out many of the function. so it acts as a super powerhouse doing all the work. and girls really only need one x to still be normal. so that's why girls with XXX end up with a disorder because it's too much. you should read the new york times article to get more info.

2007-10-18 13:47:10 · answer #2 · answered by outofwater920 4 · 0 0

It may not be obvious from candymae's answer, but males are XY and females are XX. If a female has a sex-linked disorder in one of her X chromosomes, it is sort of "balanced" out by the normal X chromosome. Males do not have this safety net because they have only one X chromosome.

2007-10-18 13:43:54 · answer #3 · answered by deedybird 3 · 0 0

No, there can be sex-linked recessive alleles on the Y chromosome as well. They are more common in males because males have one X and one Y, so they don't have another copy of either one to compensate for the recessive allele.

2007-10-18 13:44:02 · answer #4 · answered by Dr. Love 2 · 0 0

yes.. sex-linked traits are only found in the x chromosomes. that's why males are more prone to sex-linked disorders unlike females who have 2 x chromosomes.

2007-10-18 13:39:14 · answer #5 · answered by candymae_narra 1 · 0 1

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