whats the difference between a vesicle and a vacuole?

Answer 1

without copying a text book....

a vesicle...is a transport unit, like in the brain, your nuerotransmitters are stored in vesicles.

a vacuole is the water pool that exists in all plant cells

Answer 2

vesicles perform functions as storage,transport and digest of substances within a cell

vacuoles stores waste and acids in cellular metabolism and water balance

Answer 3

Vacuoles are for temporary storage.

Vesicles are like little transport pods.

Answer 4

Lool **** bio

Answer 5

In cell biology, a vesicle is a relatively small and enclosed compartment, separated from the cytosol by at least one lipid bilayer. If there is only one lipid bilayer, they are called unilamellar vesicles; otherwise they are called multilamellar. Vesicles store, transport, or digest cellular products and waste.

This biomembrane enclosing the vesicle is similar to that of the plasma membrane. Because it is separated from the cytosol, the intravesicular environment can be made to be different from the cytosolic environment. Vesicles are a basic tool of the cell for organizing metabolism, transport, enzyme storage, as well as being chemical reaction chambers. Many vesicles are made in the Golgi apparatus, but also in the endoplasmic reticulum, or are made from parts of the plasma membrane.

Some types of vesicles
Transport vesicles can move molecules between locations inside the cell, e.g., proteins from the rough endoplasmic reticulum to the Golgi apparatus.
Synaptic vesicles are located at presynaptic terminals in neurons and store neurotransmitters.
Lysosomes are membrane-bound digestive organelles that can digest macromolecules (break them down to small compounds) that were taken in from the outside of the cell by an endocytic vesicle.
Matrix vesicles are located within the extracellular space, or matrix. Using electron microscopy but working independently, they were discovered in 1967 by H. Clarke Anderson [1] and Ermanno Bonucci. [2] These cell-derived vesicles are specialized to initiate biomineralization of the matrix in a variety of tissues, including bone, cartilage, and dentin. During normal calcification, a major influx of calcium and phosphate ions into the cells accompanies cellular apoptosis (genetically determined self-destruction) and matrix vesicle formation. Calcium-loading also leads to formation of phosphatidylserine:calcium:phosphate complexes in the plasma membrane mediated in part by a protein called annexins. Matrix vesicles bud from the plasma membrane at sites of interaction with the extracellular matrix. Thus, matrix vesicles convey to the extracellular matrix calcium, phosphate, lipids and the annexins which act to nucleate mineral formation. These processes are precisely coordinated to bring about, at the proper place and time, mineralization of the tissue's matrix.

[edit] Vesicle formation and transport
Some vesicles are made when part of the membrane pinches off the endoplasmic reticulum or the Golgi complex. Others are made when an object outside of the cell is surrounded by the cell membrane.


[edit] Capturing cargo molecules
The assembly of a vesicle requires numerous coats to surround and bind to the proteins being transported. One family of coats are called adaptins. These bind to the coat vesicle (see below). They also trap various transmembrane receptor proteins, called cargo receptors, which in turn trap the cargo molecules.


[edit] Vesicle coat
The vesicle coat serves to sculpt the curvature of a donor membrane, and to select specific proteins as cargo. It selects cargo proteins by binding to sorting signals. In this way the vesicle coat clusters selected membrane cargo proteins into nascent vesicle buds.

There are three types of vesicle coats: clathrin, COPI and COPII. Clathrin coats are found on vesicles trafficking between the Golgi and plasma membrane, the Golgi and endosomes, and the plasma membrane and endosomes. COPI coated vesicles are responsible for retrograde transport from the Golgi to the ER, while COPII coated vesicles are responsible for anterograde transport from the ER to the Golgi.

The clathrin coat is thought to assemble in response to regulatory G protein. A coatomer coat assembles and disassembles due to an ARF protein.


[edit] Motor proteins
Motor proteins which change conformation and as a result move the vesicles along a set 'track'. The 'track' may consist of microtubules, for example.


[edit] Vesicle docking
Surface markers called SNAREs identify the vesicle's cargo, and complementary SNAREs on the target membrane act to cause fusion of the vesicle and target membrane. Such v-SNARES are hypothesised to exist on the vesicle membrane, while the complementary ones on the target membrane are known as t-SNAREs.

Regulatory Rab proteins are thought to inspect the joining of the SNAREs. Rab protein is a regulatory GTP-binding protein, and controls the binding of these complementary SNAREs for a long enough time for the Rab protein to hydrolyse its bound GTP and lock the vesicle onto the membrane.


[edit] Vesicle fusion
Fusion requires the two membranes to be brought within 1.5 nm of each other. For this to occur water must be displaced from the surface of the vesicle membrane. This is energetically unfavourable, and evidence suggests that the process requires ATP, GTP and acetyl-coA, fusion is also linked to budding, which is why the term budding and fusing arises.


[edit] Vesicles in receptor down-regulation
Membrane proteins serving as receptors are sometimes tagged for degregation by the attachment of ubiquitin. After arriving an endosome via the pathway described above, vesicles begin to form inside the endosome, taking with them the membrane proteins meant for degregation; When the endosome either matures to become a lysosome or is united with one, the vesicles are completely degregaded. Without this mechanism, only the extracellular part of the membrane proteins would reach the lumen of the lysosome, and only this part would be degraded[3].

It is because of these vesicles that the endosome is sometimes known as a multivesicular body. However the pathway to their formation is not completely understood. Unlike the other vesicles described above, the outer surface of the vesicles is not in contact with the cytosol.

Vacuoles are found in the cytoplasm of most plant cells. Vacuoles are membrane-bound compartments within some eukaryotic cells that can serve a variety of secretory, excretory, and storage functions. Vacuoles and their contents are considered to be distinct from the cytoplasm, and are classified as ergastic according to some authors.[1] Vacuoles are especially conspicuous in most plant cells.

[edit] Vacuole Functions
In general, vacuole functions include

Removing unwanted structural debris
Isolating materials that might be harmful or a threat to the cell
Containing waste products
Maintaining internal hydrostatic pressure or turgor within the cell
Maintaining an acidic internal pH
Containing small molecules
Exporting unwanted substances from the cell.
Enabling the cell to change shape.

Vacuoles also play a major role in autophagy, maintaining an inbalance between biogenesis (production) and degradation (or turnover), of many substances and cell structures. They also aid in destruction of invading bacteria or of misfolded proteins that have begun to build up within the cell.


[edit] Protists
Some protists and macrophages use food vacuoles as a stage in phagocytosis—the intake of large molecules, particles, or even other cells, by the cell for digestion. They are also called "storage sacs."

A contractile vacuole is used to pump excess water out of the cell to reduce osmotic pressure and keep the cell from bursting, which is referred to as cytolysis or osmotic lysis.

Note: In the euglena and some other protists, there is also a reservoir, that has the same function as a vacuole. The vacuole also stores food, waste and water, and can control the exit of waste when it is produced.


[edit] Budding yeast
In budding yeast cells, vacuoles act as storage compartments of amino acids and detoxification compartments. Under conditions of starvation, proteins are degraded in vacuoles; this is called autophagy. First, cytoplasms, mitochondria, and small organelles are covered with multiplex plasma membranes called autophagosomes. Next, the autophagosomes fuse the vacuoles. Finally, the cytoplasms and the organelles are degraded.

In a vacuole of budding yeast, a black particle sometimes appears. It is called a dancing body. The dancing body moves actively in the vacuole and appears and disappears within 10 minutes to several hours. In previous research, it was suggested but not proven that the main component of the dancing body is polyphosphate acid. But the main component has been determined to be crystallized sodium polyphosphate and its function has been studied. It is thought that its function is to supply and store phosphates in budding yeast cells.


[edit] Plants

The vacuole of Rhoeo discolor is more easily visible...
...when it's shrunk during plasmolysis.Most mature plant cells have one or several vacuoles that typically occupy more than 30% of the cell's volume, and that can occupy as much as 90% of the volume for certain cell types and conditions.[2] A vacuole is surrounded by a membrane called the tonoplast.

This vacuole houses large amounts of a liquid called cell sap, composed of water, enzymes, inorganic ions (like K+ and Cl-), salts (such as calcium), and other substances, including toxic byproducts removed from the cytosol to avoid interference with metabolism. Toxins present in the vacuole may also help to protect some plants from predators. Transport of protons from cytosol to vacuole aids in keeping cytoplasmic pH stable, while making the vacuolar interior more acidic, allowing degradative enzymes to act. Although having a large central vacuole is the most common case, the size and number of vacuoles may vary in different tissues and stages of development. Cells of the vascular cambium, for example, have many small vacuoles in winter, and one large one in summer.

Aside from storage, the main role of the central vacuole is to maintain turgor pressure against the cell wall. Proteins found in the tonoplast control the flow of water into and out of the vacuole through active transport, pumping potassium (K+) ions into and out of the vacuolar interior. Due to osmosis, water will diffuse into the vacuole, placing pressure on the cell wall. If water loss leads to a significant decline in turgor pressure, the cell will plasmolyse. Turgor pressure exerted by vacuoles is also helpful for cellular elongation: as the cell wall is partially degraded by the action of auxins, the less rigid wall is expanded by the pressure coming from within the vacuole. Vacuoles can help some plant cells to reach considerable size. Another function of a central vacuole is that it pushes all contents of the cell's cytoplasm against the cellular membrane, and thus keeps the chloroplasts closer to light.

The vacuole also stores the pigments in flowers and fruits.


[edit] Animals
Vacuoles in animals are a part of the processes of exocytosis and endocytosis. Exocytosis is the extrusion process of proteins from the Golgi apparatus initially enter secretory granules, where processing of prohormones to the mature hormones occurs before exocytosis, and also allows the animal cell to rid waste products. Endocytosis is the reverse of exocytosis. There are various types. Phagocytosis ("cell eating") is the process by which bacteria, dead tissue, or other bits of material visible under the microscope are engulfed by cells. The material makes contact with the cell membrane, which then invaginates. The invagination is pinched off, leaving the engulfed material in the membrane-enclosed vacuole and the cell membrane intact. Pinocytosis ("cell drinking") is essentially the same process, the difference being that the substances ingested are in solution and not visible under the microscope [3]

Hydropic (vacuolar) changes are of importance of identifying various pathologies, such as the reversible cell swelling in renal tubules caused by hypoperfusion of the kidneys during open heart surgery.