SAM-e on an empty stomach?

Question

I've been told it's best to take SAM-e on an empty stomach and to wait an hour after taking it to eat. Does it really make a difference?

Answer 1

SAMe is best absorbed on an empty stomach, so try to take it about one hour before or two hours after meals. If nausea or heartburn develop, take it with plenty of water.

To prevent insomnia, don't take SAMe late in the day. Most people report a mild energy boost with the supplement.

SAMe can safely be combined with other natural antidepressants such as St. John's wort, as well as most conventional antidepressants.

Purchase SAMe from a reliable company whose quality standards you trust. If improperly handled, the raw material used to make SAMe can deteriorate rapidly, making these costly supplements weak or even inactive. Look for "pharmaceutical grade" products and opt for a more stable form called "butanedisulfonate" rather than "tosylate."

To avoid a toxic buildup of Homocysteine molecules (which are formed when SAMe breaks down) be sure to take a high-quality Vitamin b complex supplement along with SAMe. These vitamins help metabolize homocysteine, which in high concentrations poses the risk for various health problems including heart attack and stroke.

A standard recommendation is to take 100 mg of a B complex once a day, regardless of the SAMe dose.

If you're particularly sensitive to medications, start out with half the recommended daily dosage and work up to the full amount after a week.

Answer 2

when you first wake up, about 30 minutes before lunch, and just before you go to bed (suggesting 3 hours after you eat dinner).

Answer 3

my sister and her boyfriend ( who are pharmicists) and they said you can take it but its a waist of money and it will probly do more harm then good!