A hemophiliac marries someone with hypercoagulation, what will their kids be?

Question

Will their kids be regular, mixed, or will 1 disease dominate the other?

Answer 1

Normal or with hypercoagulation would result with a higher chance of the child being a female, but more likely it would never survive to birth.

Hemophilia (http://en.wikipedia.org/wiki/Hemophilia) is a recessive gene and unless both parents have the condition the child will not have the condition. Even if both parents have the condition there is a chance that the recessive genes will not express themselves. But, if the child is female then it shares both chromosomes of their female parent and if she has hemophilia there will be 100% chance that she will get hemophilia.

Hypercoagulation could be tied to a person's genes. According to: http://www.anapsid.org/cnd/diffdx/hypercoagulation.html
"Hypercoagulation (thickened blood) results from fibrin being deposited in small blood vessels. Fibrin is the body's natural bandaid: strands of fibrin form across a defect (wound, tear) in the walls of blood vessels, forming a mesh that holds platelets and blood cells. This beneficial clotting of cellular matter and fibrin strands plugs the leak, so to speak, holding things together until the body starts to repair itself."

“Berg states that there are at least three possible causes for this thrombin malfunction:
Viruses, bacteria and/or parasites can activate certain antibodies in the immune system, which in this case trigger the continual production of thrombin, generating excessive SFM and fibrin.
Predispositional genetic defect in coagulation regulatory proteins (protein C, protein S, Factor VL, prothrombin gene mutation, PAI-1, Lp(a), or elevated homocysteine.
Chemical exposure can result in changes that trigger the coagulation process. “

So it is possible for a person to have hypercoagulation and give it to their children; if they have this condition though they wouldn’t have the deficiency in the proteins that causes hemophilia. Therefore you can’t have hypercoagulation and hemophilia at the same time. You could get hypercoagulation from a virus or a chemical contamination which if you had hemophilia might actually cure the condition.

If you have hemophilia and somehow contract hypercogulation there is a small chance that you will have both conditions. In which case the most dominate condition; the genetic cause would predominate or the two would cancel each other out. More likely the combination of the two would create a fatal birth defect that would prevent the fetus from developing properly.

Answer 2

actually, its only women who carry the hemophilia gene (although the disease is present almost exclusively in males). if the had a daughter, she'd carry the hemophilic gene -- and if she had a son, he'd probably have hemophilia. not too sure about the hypercoagulation though!

Answer 3

messed up.

If evolution is supposed to be good... they shouldn't breed.