I Just Saw an Ad for LOReal "Pro-Xylane" Hyaluronic Spheres, Skin Treatment, a Scam?

Question

I've Heard of Xylene, and Know how to Pronounce it, In the Ad, "Pro-Xylane" (Whatever that is) is Pronounced "Prox Ylane".

Yeah SAMI, Enough Bullsh$t Already, they Have Only Hydration.

Thanks K, I'm Surprised you Found an Abstract, and I'm Disappointed In Medline.

K, Looks Like Another Vanity Journal.

passion2share2004, "Reduce the Cause of Aging", a Scam, In my Mind, it is Advertising a Magical Solution.

I'm Sorry, I Just Heard the Ad Again On CNN, "Treat" Not "Reduce".

Thanks K, No Doubt, Pixie Dust is At Least as Effective for Aging as this is.

Answer 1

K, I actually found an abstract on this, as you appropriately say, bullsh$t “ingredient”. The abstract isn’t even intelligible, but also written in a way that appears to promote the “ingredient”--it is NOT written as an academic abstract....So, I thought this can’t be a peer-reviewed journal. Did some more searching and this guy in Italy is listed as a Founder and "Publishing Director" of the Journal of Plastic Dermatology. NO website for the journal itself that lists the review board, submission procedures etc...

Most ads p$ss me off, but THIS p$sses me off extra. Not only is it listed in ‘Medline’ (which I'm not sure why won't separate peer-reviewed and non peer-reviewed sources), but people are led to believe there IS some scientific backing, when there is only MONEY backing the "ingredient". What a crock of sh$t. There are only 49 other “articles” that exist in the “Journal of Plastic Dermatology” and they are as equally unintelligible and suspicious as that regarding “pro-xylane”.

Anyway, see for yourself. I hope I’m wrong...somehow (<--sarcasm, of course). But, here’s the link to the “author’s” (notice the quotes) webpage and the Vanity Journal’s abstract.

Scroll down to “press”:

translated version:
http://ca.search.yahoo.com/language/translatedPage?tt=url&text=http%3a//www.antoninodipietro.it/default.php%3fsezione=2&lp=it_en&.intl=ca&fr=FP-tab-web-t340

In case that link doesn't work, here's the Italian version that you can translate:

http://www.antoninodipietro.it/default.php?sezione=2

The “fake abstract”:

Di Maio, Milano; Italy.
Pro-Xylane: A 'green chemistry' product to slow the skin aging
Journal of Plastic Dermatology. Vol. 2(2)(pp 71-74), 2006

Pro-Xylane is a new anti-aging molecule for the skin developed by L'Oreal. It is a 'green' product: in fact the first ingredient is xylos, a natural sugar from beachwood sourced from western Europe, and the synthesis has only two optimised steps in which water is used as solvent. Studies performed with the Episkin model have shown that in the epidermal-dermal junction Pro-Xylane stimulates the glycosaminoglycans (GAGs) production, the sythesis of type VII collagen and the CD44 expression. In female subjects ages 50-65 after two months treatment with Pro-Xylane there was an improvement of the face wrinkles and immunohistological studies revealed an increase of condroitin 6-sulfate in the wrinkle trough.

EDIT: Yup. I don't understand why nothing is done about this. As one academic, I am insulted by the existence of these vanity journals. I mean, it trivializes empirical work, methodological rigor, confuses the heck out of society, and leads to people spending money FOR NOTHING.

Man, people interested in anti-aging? Get yourself a good, *real* dermatologist. Save your money for what WILL minimize surface wrinkles (albeit, only temporarily). Prescribed tretinoin gel, glycolic acid peels, micro-dermabrasion, botox, restylane....Tretinoin is the least costly: $20 a tube here (if you have no insurance). Relatively cheap AND efficacious...

EDIT 2: Woooo, wouldn't it be nice if wrinkles could be "treated". I think that bit might be more believable if they called it pixie dust...I mean, of course, in favour of the ridiculous name they've chosen that is suppose to sound scientific and be a "secret" on account of it's wild efficacy...don't want anyone to "know" what pro-xylane is...it's THAT good...Puuuulease....

Answer 2

Xylene is harmful to human body. Hyaluronic acid has a limited role in reducing wrinkles of skin.
So LOReal "Pro-Xylane" Hyaluronic Spheres, Skin treatment can not be accepted unless FDA clears it.
Or is it an " alternative" therapy?

Answer 3

never heard of it what's it supposted to do for you?