Which team has the record for the most runs in a regular game?

Question

also which has the record for most home runs in a regular
game.

Answer 1

Most runs by one team in a game: On June 29, 1897 The Chicago Colts (now the Cubs) (NL) beat the Lousiville Colonels (NL) 36-7.
Most runs by one team in a game, "Modern Era" (after 1900): 29, done twice. On June 8, 1950 by the Boston Red Sox (against) the St. Louis Browns and on April 23, 1955 (against the Chicago White Sox)
Most runs in a game, both teams: 49. On August 25, 1922 the Chicago Cubs defeated the Philadelphia Phillies by the score of 26 to 23.

Answer 2

The 1897 Chicago Colts (now Cubs) drubbed the Louisville Colonels, 36-7, one fine summer's day.

The Toronto Blue Jays blasted ten balls outta the park against the Baltimore Orioles on 14-Sept-1987, winning 18-3. Ernie Whitt hit three, George Bell and Rance Mulliniks had two apiece, and Lloyd Moseby, Rob Ducey, and Fred McGriff pitched in one each. Mike Hart poked one for the Orioles to bring the game total to 11. Box: http://www.retrosheet.org/boxesetc/1987/B09140TOR1987.htm