im not quite sure on this statement, can u verify if im right?

Question

The fact that Hb^S allele has remained in African populations even though it is detrimental in the homozygous state is a result of? I cant decide b/t a homozygous or heterozygote advantage, but my best guess is heterozygote advantage.

Answer 1

Heterozygous advantage.

Your own question states that "it is detrimental in the homozygous state". Detrimental is not good, so homozygous is not good.

In this case, having no allele for sickle cell leaves people at risk of dying from malaria. (homozygous normal)
Having two alleles for sickle cell leaves people with sickle cell anemia, also called sickle cell disease, and at risk of dying from sickle cell. (homozygous sickle)
Having one of each type of allele offers some protection against malaria while not causing such severe problems from sickling events. This condition is called sickle cell trait; it's heterozygous, and it's an advantage.

Answer 2

you are right

http://en.wikipedia.org/wiki/Heterozygote_advantage