In Resident Evil 4, I dont know the pattern at the Operate thing to open the door to that big house?

Answer 1

Since I don't know which door your referring to, here's a walk-through that might help:
http://www.gamespot.com/features/6116796/index.html?tag=gameguide;onlineguide;1
Hope this help. :)

Answer 2

Easy one That just look at the symbols on the door just slightly below it on the left and right side its a big clue just turn it till it looks the same (and you've seen the symbol lots of times through the game)

good luck and

Have Fun