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2007-07-18 16:14:29 · 8 answers · asked by paladius 1 in Science & Mathematics Biology

8 answers

Because I said so!
And if mama ain't happy, ain't nobody happy!

Who?, What?, Where?, When?, How?, and How many? also!

2007-07-18 16:26:34 · answer #1 · answered by ♥Sweetmusic ♥ 5 · 0 0

In diverse organisms, the Mre11 complex and phosphoinositide 3-kinase-related kinases (PIKKs), such as Tel1p and Mec1p from S. cerevisiae, are key mediators of DNA repair and DNA damage checkpoints that also function at telomeres. Here, we use chromatin immunoprecipitation (ChIP) to determine if Mre11p, Tel1p, or Mec1p affects telomere maintenance by promoting recruitment of telomerase subunits to S. cerevisiae telomeres. We find that recruitment of Est2p, the catalytic subunit of telomerase, and Est1p, a telomerase accessory protein, was severely reduced in mre11Δ and tel1Δ cells. In contrast, the levels of Est2p and Est1p binding in late S/G2 phase, the period in the cell cycle when yeast telomerase lengthens telomeres, were indistinguishable in wild-type (WT) and mec1Δ cells. These data argue that Mre11p and Tel1p affect telomere length by promoting telomerase recruitment to telomeres, whereas Mec1p has only a minor role in telomerase recruitment in a TEL1 cell.

2007-07-19 00:14:47 · answer #2 · answered by Hovik G 2 · 0 0

Why? Bakit? Ampay?

2007-07-19 02:07:23 · answer #3 · answered by jhon 2 · 0 1

I hope I could help you but you didn't really elaborate on your question.

2007-07-18 23:55:27 · answer #4 · answered by Suzy Suzee Sue 6 · 0 0

How?

2007-07-18 23:33:06 · answer #5 · answered by the_way_of_the_turtle 6 · 0 0

why not?

2007-07-18 23:17:26 · answer #6 · answered by cheyenne95129 3 · 1 0

because!!!

2007-07-18 23:21:53 · answer #7 · answered by cutewon 2 · 0 0

Why not? Thanks for the points.

2007-07-18 23:17:44 · answer #8 · answered by cattbarf 7 · 0 0

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