H.G.Khorana was awarded the Nobel Prize for?

Question

a) discovering DNA
b) chemical synthesis of DNA
c) discovering DNA polymerase
d) discovering the structure of DNA

Answer 1

b) is the correct answer. The title of his Nobel lecture is "Nucleic Acid Synthesis in the Study of the Genetic Code".

Answer 2

Khoran gets noble for describing the genetic code and how it operates in protein synthesis in 1968 along with 1968 Robert W. Holley & Marshall W. Nirenberg

Answer 3

Har Gobind Khorana (born January 9 , 1922 ) is an American molecular biologist born of Indian Punjabi heritage in British India Dr. Har Gobind Khorana, recipient of Nobel Prize for Medicine and Physiology along with Marshall Nirenberg and Robert Holley for cracking the genetic code, is a person with an unmatched perseverance and uncommon vision existent among scientists of this golden period.

Dr.khorana and his team had established that the mother of all codes, the biological language common to all living organisms, is spelled out in three-letter words:each set of three nucleotides codes for a specific amino acid, in their Nobel lecture delivered on December 12,1968. Dr.Khorana was also the first to synthesize oligonucleotides, that is, strings of nucleotides. These custom designed pieces of artificial genes are widely used in biology labs for sequencing, cloning and engineering new plants and animals.Dr.khorana's invention of oligonucleotides has become indispensable tools in biotechnology. This invention of DrKhorana has become mechanized and commercialize that anyone now can order the synthetic genes just he needs to fax the genetic sequence.

Dr.Khorana , born in Raipur, in Punjab, India in 1922, received his B.Sc and M.Sc degrees from the Punjab University in Lahore (in present day Pakistan) and his Ph.D. from the University of Liverpool, where he went in 1945 on a Government of India Fellowship. Dr. Khorana did his Post Doctoral fellowship in Zurich for period of 1948-49. He spent two years at Cambridge and his interests in proteins and nucleic acids took root that time. In 1952 he went to the University of British Columbia, Vancouver and in 1960 moved to the University of Wisconsin. He became the Alfred Sloan Professor of Biology and Chemistry at the Massachusetts Institute of Technology where he continues to work.

Dr. Khorana current research areas include Structure-Function in Rhodopsin and Protein-Protein Interactions in Amplification and Adaptation among other topics. Dr. Khorana is the one of the Scientists who do not rest on his oars, he continues to work as an Emeritus and Senior Lecturer at University of Liverpool.

Answer 4

None of these.

His Nobel citation reads "for interpretation of the genetic code and its function in protein synthesis"

Answer 5

in vitro synthesis of dna. he synthesized a dna fragment
GUGUGUGUGUGUGUGUGUGUGUG.
He then showed that the codon had 3 bases n not 2 or 4