Haemoglobin?

Question

When Haemoglobin combines with Carbon Monoxide, am I right in saying this is irreverisble and forms mono-oxyhaemoglobin?

Answer 1

It acutally forms the complex - carboxyhaemoglobin, which is much more stable than oxyhaemoglobin.

However, it is not irreversible - 100% saturated oxygen inhaled at a high enough partial pressure will be able to drive off the carbon monoxide out of the haemoglobin and reverse the process.

So the most important way of relieving CO poisoning is exposure to large amounts of fresh air, or even breathing from an oxygen tank.

Answer 2

CO combines with haemoglobin to form carboxyhaemoglobin. Carbon monoxide competes with oxygen for the binding sites of the haemoglobin molecules. The affinity of human haemoglobin for CO is about 240 times that of its affinity for oxygen. The formation of COHb has two undesirable effects: it blocks oxygen transport by inactivating haemoglobin, and its presence in the blood shifts the dissociation curve of oxyhaemoglobin to the left so that the release of remaining oxygen to tissues is impaired. Because of the latter effect, the presence of COHb in the blood interferes with tissue oxygenation considerably more than an equivalent reduction of haemoglobin concentration, for example, through bleeding. Carbon monoxide also binds with myoglobin to form carboxymyoglobin, which may disturb muscle metabolism, especially in the heart.

Answer 3

carbon monoxide when inhaled binds with haemoglobin and it forms caboxy haemoglobin.it prevents the capability of haemoglobin to carry oxygen.so cells will be devoid of oxygen.as a result of which the receiver undergoes suffocation and in high amount it can cause death too.

Answer 4

Carbon monoxide bonds very strongly to the iron in hemoglobin. When it does this it takes up all of the oxygen binding sites. (Remember hemoglobin is it protein that carries oxygen through the blood.) I do not think, however, this is called "mono-oxyhemoglobin".

Answer 5

nope,i dont think so