compared to asmall cell, large cells have more trouble ?

Question

biology

Answer 1

Large cells have more trouble distributing materials through the cell by diffusion and more trouble passing enough materials through the plasma membrane to handle the requirements of a larger cell.

Answer 2

It is widely believed that cell-size checkpoints help to coordinate cell growth and cell-cycle progression, so that proliferating eukaryotic cells maintain their size. There is strong evidence for such size checkpoints in yeasts, which maintain a constant cell-size distribution as they proliferate, even though large yeast cells grow faster than small yeast cells. Moreover, when yeast cells are shifted to better or worse nutrient conditions, they alter their size threshold within one cell cycle. Populations of mammalian cells can also maintain a constant size distribution as they proliferate, but it is not known whether this depends on cell-size checkpoints.