Has anyone tried to modify the molecule for alcohol, making it non-addictive or non-symptomatic?

Answer 1

No people have left it alone for thousands of years - they like it just the way it is!

There are however, advances in the treatments of alcoholism with the drug Nalmefene that shows promise in preventing relapse.

ref: http://alcoholism.about.com/od/meds/l/aa991103.htm