What is the one parameter that is fundamental under the biological point of view to determine a cell size?

Question

A. cell surface area, B. cell volume, C. cell length, D. cell surface/volume ratio, E. cell length/ volume ratio, or F. cell length/ surface ratio. Why?

Answer 1

D. As the cell gets larger, the surface area to volume ratio is reduced. This is a problem because the surface area is the amount of plasma membrane. There has to be a large enough plasma membrane to handle all the exchanges of gases, nutrients, wastes, and other molecules for the cell. That becomes more and more difficult as the cell gets larger.