It was known as early as 200 or 500 CE that a tendency towards fatal bleeding existed in certain families; according to the Talmud, a Jewish baby boy could be exempted from circumcision if two of his brothers had died from the procedure. The Arab physician Albucasis wrote about the same phenomenon in the 12th century CE. Dr. John Conrad Otto, an American, again wrote about it in 1803, tracing the inheritance of the disorder back almost a century in one family. Ultimately, a Swiss doctor named Hopff coined the term "hemophilia" in 1828.
2007-04-16 04:51:32
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answer #1
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answered by DavidK93 7
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When was hemophilia first recognized? Hemophilia was recognized, though not named, in ancient times. The Talmud, a collection of Jewish Rabbinical writings from the 2nd century AD, stated that male babies did not have to be circumcised if two brothers had already died from the procedure. The Arab physician Albucasis, who lived in the 12th century, wrote of a family whose males died of bleeding after minor injuries. Then, in 1803, a Philadelphia physician named Dr. John Conrad Otto wrote an account of "a hemorrhagic disposition existing in certain families". He recognized that the condition was hereditary and affected males. He traced the disease back through three generations to a woman who had settled near Plymouth, New Hampshire, in 1720. The word "hemophilia" first appears in a description of the condition written by Hopff at the University of Zurich in 1828. From Wikipedia: The first record of haemophilia is the Talmud, Jewish holy text, which states that males did not have to be circumcised if two brothers had already died from the procedure. In the 12th century, the Arab physician Albucasis wrote of a family whose males died of bleeding after minor injuries. Then, in 1803, Dr. John Conrad Otto, a Philadelphia physician, wrote an account about "a haemorrhagic disposition existing in certain families." He recognized that the disorder was hereditary and that it affected males and rarely females. He was able to trace the disease back to a woman who settled near Plymouth in 1720. The first usage of the term "haemophilia" appears in a description of the condition written by Hopff at the University of Zurich in 1828. In 1937, Patek and Taylor, two doctors from Harvard, discovered anti-hemophilic globulin. Pavlosky, a doctor from Buenos Aires, found Haemophilia A and Haemophilia B to be separate diseases by doing a lab test. This test was done by transferring the blood of one haemophiliac to another haemophiliac. The fact that this corrected the clotting problem showed that there was more than one form of haemophilia.
2016-05-21 03:16:07
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answer #3
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answered by eneida 3
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