Here is the entire paragraph about Bile production from my Anatomy and Physiology textbook:
"Red blood cells normally stay in circulation for about 120 days in males and 110 days in females. these cells have no nuclei and therefore cannot produce new proteins or divide. As their existing proteins, enzymes, plasma membrane components, and other structures degenerate, the RBCs are less able to transport oxygen and their plasma membrane becomes more fragile, Eventually RBCs rupture as they squeeze through some tight spot in the circulation.
Macrophages located in spleen, liver and other lymphatic tissue, take up hemoglobin released by the ruptured RBCs, Within the macrophages the lysosomal enzymes digest the hemoglobin to yield amino acids, iron and bilirubin. The globulin part of the hemoglobin is broken down into its component amino acids, most of which are reused in the production of other proteins. Iron atoms released from the heme, can be carried by the blood to red bone marrow, where they are incorporated into new hemoglobin molecules. The none iron part of the heme groups are converted to biliverdin and then to bilirubin which is released into the plasma. Bilirubin binds to albumin and is transported to liver cells. This bilirubin is called free bilirubin because it is not yet conjugated. Free bilirubin is taken up by the liver cells and is conjugated, or joined, to glucronic acid to form conjugated bilirubin, which is more water-soluble than free bilirubin. The conjugated biliruin becomes part of the bile, which is the fluid secreted from the liver into the small intestine."
"Anatomy and Physiology", Seeley, Stephens, Tate, Mc Graw Hills publications, 7th edition, pages 659-660.
2007-04-05 17:32:20
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answer #1
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answered by smarties 6
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no not at all, bile is an essential component in the digestion process. it is composed of bilt salts like
sodium glaucocholate
sodium taurocholate
(necessary for the emulsification of fatsinto smaller fragments thus ncreasing the surface area over which the lipase can act. i.e. breakdown of fats without which the fats are only minimally digested).these bile salts are recycled in the terminal ileum and large intestine for reuse(entero-hepatic circulation).
it also, to some extent, provides an alkaline medium in the intestine for the action of pancreatic and intestinal enzymes by sectretion of HCO3-(bicarbonate), this however is done majorly by the brunners glands of duodenum(proximal part of the small intestine) and the pancreas itself).
it does contain conjugated bilirubin,(bilirubin diglucuronide), bilirubin,a red coloured pigment is the breakdown product of RBC's heme group(mettalo-protein with 4 pyrrole rings) which is normally insoluble and needs to be conjugated to be made soluble and therefore excreted.
it is excreted in the form of stercobilin in the faeces and urobilinogen in the urine.
bilirubin is however mostly formed in the spleen and carried to the liver by albumin in the blood.
in case the liver cannot conjugate it it accumalates in the body causing 'jaundice'.
there are three types of jaundice
pre'hepatic
hepatocellular
post-hepatic
2007-04-06 00:54:05
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answer #2
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answered by rara avis 4
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According to medterms.com, "Bile is a yellow-green fluid that is made by the liver, stored in the gallbladder and passes through the common bile duct into the duodenum where it helps digest fat. The principal components of bile are cholesterol, bile salts, and the pigment bilirubin."
From the same source, bilirubin is "a yellow-orange compound produced by the breakdown of hemoglobin from red blood cells."
2007-04-05 23:49:38
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answer #3
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answered by ecolink 7
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It contains bile salts, which act as emulsifiers that aid in digestion and absorption of fats.
It also containcs pigments which are by-products of RBC destruction, not the dead blood cells themselves.
It does not contain digestive enzymes.
2007-04-05 23:51:40
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answer #4
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answered by megan_of_the_swamp 4
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Bile is made of Bile salts. These are mostly composed of cholesterol.
2007-04-05 23:49:23
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answer #5
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answered by Jen 2
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bile is a digestive fulid. it is secreted by liver, but stored in gallbladder, and it is used to digest fats into fatty acids.
2007-04-05 23:55:46
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answer #6
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answered by ASG 2
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Yes, it is an alkaline fluid.
2007-04-05 23:52:12
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answer #7
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answered by Anonymous
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