Question: Cystic fibrosis is an autosomal recessive trait in human beings. Denote the mutant allele bye c and the normal by C. What percent are expected genotypes, genotypic ratios, phenotypes and phenotypic ratios if both parents are heterozygotes.
Answer: If both parents are heterozygotes, 3 out of 4 of the offspring (children) will be normal phenotype, meaning that they will not inherit cystic fibrosis. This also means that there is a 1 out of 4 chance that the couple will have a child with the disease. In other words, there is a 75% chance that the parents will have a 75% of having normal children and a 25% chance of having children that will have cystic fibrosis. The genotypic ratio is is 1:2:1, meaning that there is one offspring that is homozygous dominant CC and one that is homozygous recessive, cc, and 2 that are heterozygous carriers: Cc, like their parents.
2007-03-30
22:23:29
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4 answers
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maxmac97
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Science & Mathematics
➔ Biology