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2007-03-29 09:42:07 · 3 answers · asked by Alpha 2 in Science & Mathematics Biology

from glycolysis or gluconeogenesis

2007-03-29 09:45:22 · update #1

3 answers

Many enzymes, include isoenzymes such as hexokinases, and Glucokinases. This is the detail on its correlation to ATP phosphorylation:

The ATP-dependent phosphorylation of glucose to form glucose 6-phosphate (G6P)is the first reaction of glycolysis, and is catalyzed by tissue-specific isoenzymes known as hexokinases. The phosphorylation accomplishes two goals: First, the hexokinase reaction converts nonionic glucose into an anion that is trapped in the cell, since cells lack transport systems for phosphorylated sugars. Second, the otherwise biologically inert glucose becomes activated into a labile form capable of being further metabolized.

Four mammalian isozymes of hexokinase are known (Types I - IV), with the Type IV isozyme often referred to as glucokinase. Glucokinase is the form of the enzyme found in hepatocytes. The high Km of glucokinase for glucose means that this enzyme is saturated only at very high concentrations of substrate.

2007-03-29 09:51:08 · answer #1 · answered by Bryant M. 4 · 0 1

The general class of enzymes that does this is "Ligases". The only enzyme I can see in gluconeogenesis that does this is pyruvate carboxylase. None of the enzymes in glycolysis are ligases

2007-03-29 16:59:06 · answer #2 · answered by hcbiochem 7 · 0 0

no clue...

2007-03-29 16:45:31 · answer #3 · answered by Anonymous · 0 0

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