biologist help!!(lol its an easy question)?

Question

I wanna ask a question..

In the blood ABO test....

as we know blood type AB is the universal recipient while blood type O is universal donor....and if we dindt donate the or recieve the suitable type of blood our blood will agglutinate and it would be fatal.

Ermmm...once there was a question in my reference book.

If blood of group AB is mix with the blood group O in a test tube,will it agglutinate since:-

a) If a person donate blood O to AB it would be fine
b) but if blood group AB is donated to blood group O than it would agglutinate..

this is very confusing can some1 help me on how to define whether it will agglutinate or not if its in the state of mixture in a test tube..

thx i need this in my exam tommorow

Answer 1

agglutination occurs if there is an antibody in the body that can recognize the antigen entering the body.antigen is present on the RBCs and antibodies are present in the blood plasma. now a person with blood group AB has no antibodies against A or B or O(in O however there is no antigen and so it doesn't present an antigen to the antibodies present in the blood, therefore it is a universal donor) and hence there is no question of blood agglutination, if any of the blood types are infused. however though blood group O has no antigens the blood does have antibodies for A B and AB. hence if any blood type other than O enters the body there will be an antigen-antibody reaction and the blood will agglutinate.
Hope that helps.
The explanation is oversimplified though.

Answer 2

Before transfusion into a patient blood is separated into red blood cells and plasma. The red blood cells get transfused and do not contain any antibodies. The donor body, however contains antibodies. So if you add red blood cells from an AB donor to a O-type patient, the antibodies present in the patient will react against the antigenes A+B present on the red blood cell.
If you give red blood cells from a 0-type donor to a person of the blood group AB, the recipient does not have antibodies against blood type 0 (nor against A or B), therefore the recipient will be fine.
Look at the table at the end of this page and look not only at antigen, but also antibodies.
But please try to use proper grammar and spelling, it will make it much easier to read and understand your question. Or do you want me in the future to misspell everything in my answer to make it hard for you to understand?

Answer 3

Putting it very simply, if the body's immune system doesn't recognize something, it treats it as an invader and will cause "foreign" blood cells to agglutinate.
The surface membrane of red blood cells can either contain a protein of type A, or a protein of type B, or both, or neither (resulting in blood types A, B, AB or O respectively).
If you have blood type O, this is simply saying your red blood cells have an absence of either the type A or the type B protein. Obviously then, you can see that this person's immune system has never heard of cells with type A or type B proteins, so will attack and agglutinate any blood from a donor with blood type A, B or AB.
A person with blood type A will have an immune system which doesn't recognize the type B protein, so will attack any blood from a donor with blood type B or AB. A donor with blood type O, however, doesn't have either of these proteins, so it will "slip through" the checks of the immune system, and this blood will be accepted.
The same goes for a person with blood type B, who can't receive blood from either an A or an AB but can receive from O.
A person who is blood type AB has an immune system which recognizes both proteins, so no blood it receives will be viewed as "foreign", and the person can receive blood from all donors without rejection.


btw - the same applies to the Rhesus factor (+ or -) - it's just an addtional protein which red blood cells either have (+) or don't have (-)

Answer 4

When the book talks about universal donor and universal acceptor, they are refering to washed packed red blood cells. You are absolutely correct in assuming that if you mix whole blood from AB person with whole blood from O peson it will agglutinate. But if you mix washed packed red blood cells from an O person (the packed red blood cells do not contain antibodies to A/B/AB antigens) with blood from an AB person, there will be no agglutination because the AB person doesn't make antibodies and the washed packed RBC of the O person had the antibodies washed out already.

Answer 5

blood group AB has both antigens a, b and no antibodies where as blood group O has no antigens and both anti bodies. hence agglutination occurs when AB is added to O.

Answer 6

o is the universal DONOR not RECIEVER..it can receive ONLY o
AB can receive all types including o

Get it?