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2007-03-20 04:36:24 · 1 answers · asked by Anonymous in Education & Reference Homework Help

1 answers

The life cycle of Plasmodium is very complex. Sporozoites from the saliva of a biting female mosquito are transmitted to either the blood or the lymphatic system[1] of the recipient. It is worth noting that for some species the vector may not be a mosquito.

Only female mosquitoes bite. Aside from blood both sexes live on nectar. One or more blood meals are needed by the female for egg laying as the protein content of nectar is very low.

The sporozoites migrate to the liver and invade hepatocytes. This latent or dormant stage of the Plasmodium sporozoite in the liver is called the hypnozoite. From the hepatocytes, the parasite replicates into thousands of merozoites, which then invade red blood cells.

Here the parasite grows from a ring-shaped form to a larger trophozoite form. In the schizont stage, the parasite divides several times to produce new merozoites, which leave the red blood cells and travel within the bloodstream to invade new red blood cells. Most merozoites continue this replicative cycle, but some merozoites differentiate into male or female sexual forms (gametocytes) which are taken up by the female mosquito.

In the mosquito's midgut, the gametocytes develop into gametes and fertilize each other, forming motile zygotes called ookinetes. The ookinetes penetrate and escape the midgut, then embed themselves onto the exterior of the gut membrane. Here they divide many times to produce large numbers of tiny elongated sporozoites. These sporozoites migrate to the salivary glands of the mosquito where they are injected into the blood of the next host the mosquito bites. The sporozoites move to the liver where they repeat the cycle.

2007-03-20 09:52:17 · answer #1 · answered by shitstainz 6 · 0 0

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