Where does the uracil in RNA come from?

Question

I'm just curious. No bombardment please.

Answer 1

Like the other nucleotides in nucleic acids, cells can either reuse uracil salvaged from other pathways (e.g. the degradation of mRNA) or synthesize the uracil from scratch. Uridine (uracil + sugar and phosphate) is a precursor to thymine and cytidine, so it will constantly be available.

Answer 2

Uracil is a pyrimidine which is common and naturally occurring.

Uracil was originally discovered in 1900 and it was isolated by hydrolysis of yeast nuclein that was found in bovine thymus and spleen, herring sperm, and wheat germ.

Uracil also recycles itself to form nucleotides by undergoing a series of phophoribosyltransferase reactions

It base pairs with adenine and is replaced by thymine in DNA. Methylation of uracil produces thymine.

There are many laboratory syntheses of uracil available. The first reaction is the simplest of the syntheses, by adding water to cytosine to produce uracil and ammonia.
The most common way to synthesize uracil is by the condensation of maleic acid with urea in fuming sulfuric acid. Uracil can also be synthesized by a double decomposition of thiouracil in aqueous chloroacetic acid.

Answer 3

Uracil is produced by chemical degradation of cytosine inside the cell.

Answer 4

its inside the cell..