If a person drink 350ml of 300 mOsm NaCl solution.How will it affect the renal physiology?

Answer 1

I'm no expert on this at all, so this is more of a guess. But, seeing as it's iso-osmotic with blood, it would simply increase blood pressure. Increased blood pressure would decrease activity of the renin-angiotensin system. That would decrease sympathetic activity, decrease Na/Cl reabsorption, decrease aldosterone release, and decrease water resorption.

Seems like a good guess to me.