How is karyotyping related to Amniocentesis?
Need help more on the karyotyping side. Thanks :)
2007-03-01 11:58:34 · 2 answers · asked by lvlambs 2 in Pregnancy & Parenting ➔ Pregnancy
Karyotyping is a test to identify chromosome abnormalities as the cause of malformation or disease. This test can:count the number of chromosomes and look for structural changes in chromosomes
The results may indicate genetic changes linked to a disease.
The test can be performed on a sample of blood, bone marrow, amniotic fluid, or placental tissue.
Chromosomes contain thousands of genes that are stored in DNA, the basic genetic material. The specimen is grown in tissue culture in the laboratory. Then, the cells are harvested, and the chromosomes are stained and viewed under a microscope. They are photographed to provide a karyotype, which shows the arrangement of the chromosomes.
Certain abnormalities can be identified through the number or arrangement of the chromosomes.
The blood test is usually performed to evaluate a couple with a history of miscarriages or to evaluate an abnormal appearance of the body that suggests a genetic abnormality. The bone marrow or blood test can be done to identify the Philadelphia chromosome that is present in 85% of those with chronic myelogenous leukemia (CML). The amniotic fluid test is done to evaluate a developing fetus for chromosome abnormalities.
2007-03-01 12:14:35 · answer #1 · answered by InAMoment 3 · 0⤊ 0⤋
karyotyping is a test to identify chromosome abnormalities as the cause of malformation or disease. It can count the number of chromosomes and check for structural changes.
2007-03-01 12:18:13 · answer #2 · answered by krispeds 3 · 0⤊ 0⤋