what is an endonuclease?

Question

a link would be helpful too

Answer 1

en·do·nu·cle·ase (ěn'dō-nōō'klē-ās', -āz', -nyōō'-) Pronunciation Key
n. Any of a group of enzymes that catalyze the hydrolysis of bonds between nucleic acids in the interior of a DNA or RNA molecule.

any of a group of enzymes that degrade DNA or RNA molecules by breaking linkages within the polynucleotide chains.

a nuclease that cleaves nucleic acids at interior bonds and so produces fragments of various sizes

an enzyme that breaks down a nucleotide chain into two or more shorter chains by cleaving the internal phosphodiester bonds—see RESTRICTION ENDONUCLEASE; —compare EXONUCLEASE


Any of a group of enzymes that catalyze the hydrolysis of phosphodiester bonds between nucleic acids in a DNA molecule or an RNA sequence.

Answer 2

Endonucleases are enzymes that cleave the phosphodiester bond within a polynucleotide chain. Restriction endonucleases (Restriction Enzymes) cleave DNA at specific sites, and are divided into three categories, Type I, Type II, and Type III, according to their mechanism of action. These enzymes are often used in genetic engineering to make recombinant DNA for introduction into bacterial, plant, or animal cells.

http://en.wikipedia.org/wiki/Endonuclease


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Answer 3

Or, in simpler non-cut and paste terms, an endonuclease is any enzyme that cleaves the bonds between sugars within a DNA molecule.

Answer 4

Endonucleases cut DNA internally at specific locations (each endonuclease recognizes a unique DNA sequence). They should not be confused with exonucleases (e.g. DNAse, RNAse) which indiscriminantly remove nucleotides from the end of a nucleic adic.