Why does when a cell replicates within a body, age occurs....?

Question

but when the same genetic material (half from the mum, half from the dad) becomes the fertilized egg, the "age" of the cell becomes a non factor?

Answer 1

One of the more popular theories compares it to copier machines. Every time a new cell is created, the DNA being replicated may contain more errors than the original had.

When we're born, DNA strands have long endings of basically neutral space which buffer them from damage. As we age, those blank tails wear down, giving rise to more chances for errors to occur.

These "telomeres" exist in much greater length in newborns than adults. Thus, an adult eventually reaches a point where the telomere length is no longer sufficient to keep DNA damage from resulting when cells split and reproduce. In this model, aging is literally the result of corrupted DNA.

It should be noted that there's a trade-off for humans here: if the telomeres were extended indefinitely, it can give rise to greater rates of cancer (demonstrated even in our modern, aging populace).

Answer 2

The germ cells, namely sperms and ovums, DO age and die, that is why they have life span. When they fused [fertilised], the 'aging' process, actually growth, is still continuous. Germ cells are newly produced cells when they fused in the oviduct. Hence, they are analogous to a baby, still very young. Then, cells replicates until the zygote turns into an embryo, then into foetus. Till then, most cells are still very active and boisterous. When a baby begin to grow up, the early cells aged and die, a natural process indeed. So, you cannot say that the 'age' is a non-factor. When cells replicates, their telomere caps on the terminals of DNAs will slowly worn away. This is due to the mechanism of DNA replication. The ends of DNA [telomere cap] will not be replicated for each round of replication. SInce telomeres do not code for any proteins, they are meaningless, serving only as a protection. But as the terminals thin away without being replicated, the telomeres will be soon gone. Then, the part of DNA which codes for protens will begin to wear too. This contributes to cell aging.

Answer 3

The way I understand it, the process of aging is related to the slowdown of cell replication in the body. This slowdown is evolution's response to cancer. The older you get, the more genetic damage accumulates in your cells due to external factors (food you eat, polutants you inhale, etc etc). As these defects pile up, there is a greater chance of mutations (which is basically what leads to cancerous cells). So the body reacts by slowing down the replication rate of your cells as you get older. Thus your body does less to regenerate itself and you age, but this effect is a result of the body trying to lower the cancer risk to something that will, in most instances, not interfere with you until after child bearing age.

Answer 4

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Answer 5

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Need to do more study on the subject.