Prevention
Although improved sanitation on the public level and fastidious hygiene on the personal may help reduce the spread of polio, the only real way to prevent the disease is with the polio vaccine.
However, efforts to banish polio worldwide face major obstacles. Some communities in parts of the world, concerned about the safety of the vaccine, have resisted immunizations. In other areas, war and civil disorder prevent health workers from reaching vulnerable populations. In addition, travelers in under-vaccinated countries may unwittingly carry the virus into previously polio-free zones.
Vaccine history: A heated rivalry
Two researchers, Jonas Salk and Albert Sabin, were contentious rivals in the effort to produce the first and safest vaccine. Salk got his vaccine, which used an inactivated form of the virus, into production first, and it was tested in a field trial in 1954. The trial of the Salk vaccine — poliovirus vaccine inactivated (IPV) — was unprecedented, both in scope and sheer audacity: an unproved and potentially dangerous vaccine was given to 650,000 young children, the fear of polio apparently greater than fear of the drug.
Sabin was so convinced that Salk's approach was wrong that he tried, unsuccessfully, to block the trial. But Salk's drug was declared safe and effective at the conclusion of the tests, and mass public immunizations began almost immediately. IPV had its drawbacks, however. It wasn't 100 percent effective, it had to be given in a series of three injections and there was concern that it didn't provide lifelong immunity.
By the time Sabin's vaccine was licensed in 1962, polio cases and the hysteria surrounding the disease had both dropped dramatically, and the public was ready for something different. Sabin's oral polio vaccine (OPV) fit the bill since it conferred lifelong immunity and was simple to administer because it was given by mouth.
But the Sabin vaccine used a weakened form of live virus, and though that provided the added benefit of transferring immunity to unvaccinated people in the community, it also caused an average of eight cases a year of actual polio. For a time, doctors used a combination of the two vaccines, but the Sabin vaccine was discontinued in the United States in 2000, although it's still used in the global eradication campaign.
2007-02-19 21:37:29
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answer #1
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answered by Duke 2
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Polio vaccination is the most direct preventative medication. I must say that it's not really an issue here in the US.
2007-02-19 21:40:41
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answer #3
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answered by Porterhouse 5
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