Can you make a web layout using Paint.net?

Answer 1

Technically yes, you could design a web site layout and create graphics for your site in any graphics program, even one as primitive as Paint.NET. But they won't turn out all that great, and you'll still need to do all the coding yourself of course.

Answer 2

I dn't think so since that URL re-directs to:

http://www.warrenpaint.com/index.htm

Which is a paint manufacturer