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A severe inherited condition arises from the failure to produce an enzyme that breaks down glycoprotein in cells. the condition can be diagnosed from an electron micrograph of a patient's cells. Which abnormality would be observed in these cells?

A. an incomplete chromosome due to lack of gene
B. larger lysosomes due to accumulation of glycoprotein
C. less endoplasmic reticulum due to a reduction in protein synthesis
D. thinner cell surface membrane due to lack of glycoprotein

2007-02-17 14:20:41 · 3 answers · asked by Anonymous in Science & Mathematics Biology

3 answers

I'd go with B. Lysosomes are involved in membrane cycling. I guess the lysosome might swell if they can't break down glycoproteins.

It's not A...you can;t see a mutation with an EM.
It's not C...the ER is making thousands of proteins...one less is not going to effects its ultrastructure
It's not D...glycoproteins would be hard to see with an EM and they would be larger not smaller if anything

I'm just a botany professor...this is a bit beyond my expertise. I'm 90% sure.

2007-02-17 14:45:26 · answer #1 · answered by ivorytowerboy 5 · 1 0

I'll agree with the Botany prof (and the first poster too). Just be sure you understand why, or else you'll wind up in trouble come exam time.

Not my area of expertise either, I do genetics, but I have done some EM work through a practical course. So A) is totally wrong, you'll NOT be able to see the change on an EM, D) is wrong as you don't get that kind of resolution. I agree with the prof about C, too. So that leaves us with B.

2007-02-18 00:40:40 · answer #2 · answered by melanie 5 · 0 0

Do your own homework!

2007-02-17 22:23:23 · answer #3 · answered by Anonymous · 0 0

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