Preparation of Propanal and Aldol condensation?

Question

Where I can find procedure to carry out this orgchem experiments

i try googling it but i can't find anything

starting material is propanol

Answer 1

Propanal is mainly produced through the hydroformylation, by combining synthesis gas (carbon monoxide and hydrogen) with ethylene using a metal catalyst:

CO + H2 + C2H4 → CH3CH2CHO


An Aldol condensation is an organic reaction where an enolate ion reacts with a carbonyl compound to form a β-hydroxyaldehyde or β-hydroxyketone followed by dehydration to a conjugated enone.

The first part of this reaction is an aldol reaction, the second part an elimination reaction. Dehydration may be accompanied by decarboxylation when an activated carboxyl group is present. The base used in this reaction is a strong base like potassium t-butoxide, potassium hydroxide or sodium hydride .

Answer 2

Buy Propanal ... or you can make it from propanol or propanoic acid with a simple oxidation (PCC) or reduction (1.LiAlH4/2.H20).

It's kind of funny you're looking at an aldehyde and an aldol. In my synthesis class, the professor keeps lecturing us: "Don't use an aldehyde and a strong base .... you'll just get an Aldol product" ... anyway.

You can find Aldol procedures on Scifinder scholar or by searching Journal of Organic Chemistry (acs publication)

In terms of books, I'd recommend Harwood's "Experimental Organic Chemistry" or Vogel's "Practical Organic Chemistry".

Answer 3

in chemistry books and other related websites