Presumably the donor stem cells would contain the donor's own genetic information. Would the stem cell transplantee require the same drugs that prevent organ rejection or would the stem cells adapt/take on the new host DNA?
2007-02-07 23:00:41 · 2 answers · asked by Anonymous in Science & Mathematics ➔ Biology
Stem cells are Pro-cells which haven't differentiated into any particular cell-type. It is highly differentiated cells that have individual-specific antigens (HLAs) present on the surface. Hematopoietic Stem Cells in comparison have less of these and thus a sibling match can work with reduced drug intake.
So the bottom-line is, yes, you would still need drugs, but the chances of survival are much higher (Ref).
2007-02-07 23:15:05 · answer #1 · answered by axe 2 · 1⤊ 0⤋
Not quite true. The stem cells would contain the donor's DNA, but that would be removed and replaced with the hosts DNA from the area of the body that the stem cell would need to become. The stem cell would then divide into those types of cells. There would be no need for rejection medicine at al.
2007-02-08 07:09:29 · answer #2 · answered by Christopher L 3 · 0⤊ 1⤋