You have to keep in mind that 75-80% of what we know about cell cycle and mitosis comes from biology of the budding yeast, which led Sir Paul Nurse and Sir Tim Hunt (together with Dr Lee Hartwell) to win the Nobel prize for Medicine in 2001). The general mechanisms must, therefore, be conserved between yeast and high eukaryotes!
Yeasts such as Saccharomyces cerevisiae (but not S. pombie!) reproduce by budding. Instead of division into two, the mother cell develops an outgrowth or bud. After a daugther nucleus has moved in, which however cannot be seen under the light microscope, the bud separates from the mother cell. The individual daughter cells develop at different positions at the cell wall of the mother cell. Before the budding can happen, however, the process that will go on inside the yeast cell is very much like mitosis in higher eukaryote cells (and in Pombie cells). In this sense, chromosomes need to have replicated into 2 sister chromatides, the nucleus dissolves, the mitotic spindle is formed and the chromosomes allign onto the mitotic spindle plate. Also, all the major control complexes, in charge of progression through mitosis are conserved (cdc kinases and spindle checkpoint complexes such as Aurora B kinase and PLK). The major difference is that the mitotic spindle is not alligned in the centre of the cell, and does not appear to be symmetrical. Moreover, during anaphase, the mitotic spindle presents four sequential activities: alignment at the mother-daughter junction, fast elongation, translocation into the bud, and slow elongation.
Have a look at this old paper:
Kinetics of spindle pole body separation in budding yeast.
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=40871
2007-02-07 18:03:12
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answer #1
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answered by Jesus is my Savior 7
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Mitosis is a part of cell division - dividing a doubled nucleus into two equal parts so the cell can divide into two daughter cells.
Budding is a form of asexual reproduction in which an organism just grows a little bump and the bump containues to develop into a new organism. It takes mitosis and cell division to make the bud and mitosis and cell division to add cells to the bump.
Animals that reproduce by budding include sponges and cnidarians (jellyfish, sea anemone, hydra, ...)
Yeast is a unicellular organism that reproduces asexually by budding, but it's a matter of one cell making one new cell.
2007-02-07 15:27:42
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answer #2
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answered by ecolink 7
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Cell division means one cell turns into one or more cells. Cell differentiation means different types of cells eg.algae,humans,etc.
2016-03-28 21:40:14
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answer #3
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answered by Anonymous
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