2007-02-07 04:08:57 · 4 answers · asked by Anonymous in Science & Mathematics ➔ Biology
Wikipedia and other sources might not be that explicit. Their explanation may be more sophisticated for you. Assuming that I would like to explain in the following manner:
Suppose you have determined the aa sequence of alpha chain of goblin of haemoglobin of man, monkey, horse and donkey. You have arranged the sequence beginning from from the N terminal to C terminal in the following manner:
Man: NH2- gly-lys-ala-asp-val-try-lys-gly-----CooH
Monkey: NH2-gly-lys-val-asp-val-try-lys-gly-----CooH
Horse: NH2-gly-glu-ala-leu-val-try-lys-gly-----CooH
Donkey NH2-gly-glu-ala-leu-val-try-arg-gly-----CooH
If you compare the sequence, you will find that between man and monkey there is one difference, and between man and horse there are two differences.This means that the man and monkey are closer in the sense that during the course of evolution, that is , the time when they diverged there was one point mutation. But man and horse diverged long back in time and hence two differences. The differences imply the mutation/ million years or so.
2007-02-07 14:02:54 · answer #1 · answered by Ishan26 7 · 0⤊ 0⤋
That's a pretty vague question. There are lots of programs online that will align sequences for you. i'd look at expasy.org if that's what you want to do. they have links to all kinds of tools for genomics, proteomics, etc. NCBI also has BLAST searches and such that you can do, but expasy would be my first recommendation for you.
2007-02-07 04:30:05 · answer #2 · answered by raerae_2001 3 · 0⤊ 0⤋
You need to refer to appropriate books on bioinformatics for understanding the subject. Partial understanding from the blog answers could mislead you and land in trouble in case you are serious about learning.
2007-02-09 00:08:21 · answer #3 · answered by Ganesh 4 · 0⤊ 0⤋
http://en.wikipedia.org/wiki/Sequence_alignment
Go to this page you will get lots of information
hope it helps
2007-02-07 04:31:22 · answer #4 · answered by MSK 4 · 0⤊ 0⤋