What means the twelfth house in the acquarius?

Answer 1

The twelfth house can refer to karma and spiritual matters.

Aquarius (Indifferent and Unconventional)
You may appear to be aloof and you have a basic urge to be different. You are a thinker (air) and you are very persistent in what you do (fixed). You follow your own path and do what you want to do (active). You may be inventive or unconventional. However, you do not change easily (fixed). You are sure and confident about what you believe. (I know). You are concerned not so much about yourself, or your family, as you are concerned about the world, and may value your friends more than anything else.

Love & Blessings
Milly

Answer 2

twelfth house we find areas of life that tend to place one away from the rest of society. Monasteries naturally fall into this category. Sometimes this isolation is self imposed. Any planets in this house may represent something that the individual either doesn't have a clear view of or doesn't want a clear view of. This is also the house of spiritual inspiration, cosmic consciousness and enlightenment. The twelfth house corresponds to Pisces and so any planets in this house function with some underlying Pisces style.