2007-02-04 07:59:31 · 3 answers · asked by Anonymous in Science & Mathematics ➔ Biology
The nucleic acids are very large molecules that have two main parts. The backbone of a nucleic acid is made of alternating sugar and phosphate molecules bonded together in a long chain.
Since a monophosphate ester of this kind is a strong acid (pKa of 1.0), it will be fully ionized at the usual physiological pH (ca.7.4) and therefore will have a negative charge.
2007-02-04 08:21:23 · answer #1 · answered by Jesus is my Savior 7 · 1⤊ 0⤋
DNA has a negative charge because of the sugar phosphate backbone. The phospate group has is PO4-2 it has a 2- charge. That is why when doing gel electrophoresis, you insert the DNA at the - end of the gel and it moves toward the + end.
2007-02-04 18:37:45 · answer #2 · answered by Linnea L 3 · 0⤊ 0⤋
Because they come from your parents, who are always on your case about something or other.
Or maybe that's just my parents.
Oh, no, wait! It's because they bounce checks all the time! Buh-dum-psssshhhh! HA!
I don't know. I didn't realize they did.
2007-02-04 16:03:47 · answer #3 · answered by SlowClap 6 · 0⤊ 3⤋