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When an embrionic stem cell is implanted to a region in our body, it can turn into the cell needed for that region? This cant b done in vitro. Wad do u think that drives the differentiation?

2007-02-03 05:15:07 · 2 answers · asked by computer(easy) 1 in Science & Mathematics Biology

when an embrionic stem cell is implanted to a specific organ, it is differentiated into the cell of that organ. This cant b done in vitro, do u know why? Wad stimulates the differentiation?

2007-02-03 05:17:14 · update #1

2 answers

Stem cells are primal cells common to all multi-cellular organisms that retain the ability to renew themselves through cell division and can differentiate into a wide range of specialized cell types.
The rigorous definition of a stem cell requires that it possesses two properties:

* Self-renewal - the ability to go through numerous cycles of cell division while maintaining the undifferentiated state.
* Unlimited potency - the capacity to differentiate into any mature cell type. In a strict sense, this makes stem cells either totipotent or pluripotent, although some multipotent and/or unipotent progenitor cells are sometimes referred to as stem cells.

These properties can be illustrated in vitro, using methods such as clonogenic assays, where the progeny of single cell is characterized.[4][5] However, in vitro culture conditions can alter the behavior of cells, making it unclear whether the cells will behave in a similar manner in vivo.

stem cells remain undifferentiated from environmental cues in their particular niche. Stem cells differentiate when they leave that niche or no longer receive those signals. Studies in Drosophila germarium have identified the signals dpp and adherins junctions that prevent germarium stem cells from differentiating.

The signals that lead to reprogramming of cells to an embryonic-like state are also being investigated. These signal pathways include several transcription factors including the oncogene c-Myc. Initial studies indicate that transformation of mice cells with a combination of these anti-differentiation signals can reverse differentiation and may allow adult cells to become pluripotent. However, need to transform these cells with an oncogene may prevent the use of this approach in therapy.

During differentiation, certain genes are turned on, or become activated, while other genes are switched off, or inactivated. This process is intricately regulated. As a result, a differentiated cell will develop specific structures and perform certain functions.

2007-02-03 07:15:37 · answer #1 · answered by MSK 4 · 0 0

purely desire to characteristic a splash... cellular branch : improve sort of that particular cells.eg-->mitosis and mieosis ( a million cellular supply 2 or 4 daughter cells) cellular differentiation : much less astounding cellular will become a extra astounding cellular.eg-->stem cellular (not probably good,no particular function) differentiate into blood cellular ( extra specialize,has its particular function)

2016-12-13 08:00:13 · answer #2 · answered by casco 4 · 0 0

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