What can cause a change in the 3-D shape of an enzyme?

Answer 1

Protein conformation: refers to the three dimensional shape of a protein molecule. This shape is important to its function. If the conformation is changed, even slightly , then the function of the protein changes.

Levels of Protein structure:

1. Primary: refers to the unique sequence of amino acids in the protein. All proteins have a special sequence of amino acids, this sequence is derived from the cell's DNA.

2. Secondary : the coiling or bending of the polypeptide into sheets is referred to the proteins secondary structure. alpha helix or a beta pleated sheet are the basic forms of this level. They can exist separately or jointly in a protein.

3. Tertiary: The folding back of a molecule upon itself and held together by disulfide bridges and hydrogen bonds. This adds to the proteins stability.

4. Quaternary: Complex structure formed by the interaction of 2 or more polypeptide chains.

Major causes of protein denaturation are: organic solvents being added to them, heat, and change in pH.

Answer 2

The change in one or several amino acids making up the polypeptide chain, thus causing different bondings at different sites. The shape of the protein is twisted into a different shape, having different function.

Answer 3

a common cause of the denaturation of a protein is heat. (this is why when you cook an egg, the white goes from clear to white - you are denaturing the protein and changing the protein's shape)

Answer 4

When the enzyme does a barrel roll.

Answer 5

I think the answers are C, D, and D

Answer 6

de-naturation