What is the difference between sickle-cell anemia and sickle-cell trait?

Answer 1

The difference between being homozygous for this recessive trait, or being a heterozygous carrier of b chain point mutation. One amino acid difference in the protein hemoglobin make-up.

Answer 2

Hemoglobinopathies are team of ailments result from a disease in hemoglobin shape and that incorporate the sickle cellular anemia ( the two have a similar which skill and development ), so there is a few style of mutation interior the form of hemoglobin which could be inherited via autosomal recessive inheritance. which skill the the two discern must be provider or diseased to have a diseased infant (with scientific indications) if in user-friendly terms between the discern is affected the babies would be distributors and there are various information approximately that. the characteristic of this ailment is forming a normal shape of pink blood cellular that would reason severe problems. you need to comprehend that the traditional disc shape of pink blood cells is important for the pass of blood interior the vessels. thalassemia is ailment result from a disease particularly gene deliver approximately shrink of hemoglobin formation (shrink extensive style or none) so that's concerning to the numbers of hemoglobin and it is inherited by skill of a similar way of sickle cellular anemia. there are categories of thalassemia in accordance to the severity of the ailment and additionally to the diploma of the disease. the two are varieties of anemia because of the fact the hemoglobin (carry the oxygen to the tissues) isn't functioning properly because of disease in shape (hemoglobinopathis; sickle cellular anemia) or disease in extensive style (thalassemia). and returned there's a great style of information approximately it. i wish you recognize and stable luck.

Answer 3

Just to expand, the anemia disease is due to homozygous mutants (that is, both gene copies are defective). The trait means you are a carrier, you have one copy which is defective. If you mate with a person who also is a carrier, your offspring have a 1/4 chance of getting the disease.