what is the relationship between genes, proteins, x chromosomes and the haemophillia disorder?

Answer 1

If this is a homework question then you are going to have to research more on this than what you are going to get off Yahoo Answers!

Genes are made up of proteins situated on the double helix strands of DNA. DNA is translated into messenger RNA (mRNA) which is transcripted into a series of amino acids which make up proteins. (So here you may need to have an understanding of DNA, mRNA, base pairs, translation, codons, transcription, and amino acids).

The haemophilia part is more simple:-
Haemophilia is carried on the X chromsosome. Males have only one X chromosome inherited from the mother and one Y chromosome inherited from the father. Females have two X chromosomes, one from mother and one from father. Haemophilia is a recessive gene carried on the X chromosome. For a female to have the haemohpilia condition she would need to inherit the X chromosome with the haemophilia gene from her mother and the X chromosome from her haemophilia sufferer father. A male would have to have inherited the X chromosome from his mother which has the gene.

If a female was to inherit only one gene on one of her X chromosomes, then the dominant normal gene would mean she did not have the condition but would be a carrier.

Haemophilia occurred due to probably many mutations in the series of amino acids (proteins) on the X chromosome. The 'normal' gene in very basic terms is for the blood clotting factor in the blood, but the haemophilia gene means that the blood clotting factor is missing.

Hope this is ok!

Answer 2

Genes are made up of proteins situated on the double helix strands of DNA. DNA is translated into messenger RNA (mRNA) which is transcripted into a series of amino acids which make up proteins. (So here you may need to have an understanding of DNA, mRNA, base pairs, translation, codons, transcription, and amino acids). The haemophilia part is more simple:- Haemophilia is carried on the X chromsosome. Males have only one X chromosome inherited from the mother and one Y chromosome inherited from the father. Females have two X chromosomes, one from mother and one from father. Haemophilia is a recessive gene carried on the X chromosome. For a female to have the haemohpilia condition she would need to inherit the X chromosome with the haemophilia gene from her mother and the X chromosome from her haemophilia sufferer father. A male would have to have inherited the X chromosome from his mother which has the gene. If a female was to inherit only one gene on one of her X chromosomes, then the dominant normal gene would mean she did not have the condition but would be a carrier. Haemophilia occurred due to probably many mutations in the series of amino acids (proteins) on the X chromosome. The 'normal' gene in very basic terms is for the blood clotting factor in the blood, but the haemophilia gene means that the blood clotting factor is missing.

Answer 3

The X chromosome is one of the sex chromomsomes - females have two, one from each parent and males have one, from their mother their other sex chromosome from their father is the Y.

Genes are the units of DNA sequence that code for functional proteins. The gene for factor VIII is on the X chromosome. Males have one copy of this gene but females have two, although in every female cell one of the chromosomes is switched off so that both sexes have equal amounts of X information.

In the case of haemophilia the factor VIII is non-functional as a result of mutation in the genetic code and either no factor VIII or a non-functioning protein is produced. Factor VIII is one of the proteins involved in blood clotting. Blood clotting is a chain of events called a cascade and one missing protein prevents the whole process from occurring. This condition is haemophilia.

Because it is on the X-chromosome it is far more prevalent in males than females as they have no second X chromosome and normal gene to produce functioning protein when they carry a damaged copy. Males inherit the illness from a carrier mother whereas females require both a carrier mother and affected father to inherit the disease.

This is one of the genetic illnesses famously suffered by the European Royal Family, Queen Victoria was a carrier and her children carried it on to other parts of the family. The ultimate source of the mutation has been traced to "The august testicles of Queen Victoria's grandfather'.

Answer 4

genes contain the dna that codes for proteins. hemophilia is sex-linked, which means that it is passed to males more than females. males= XaY, females=XaXa

Answer 5

no need to answer, already sound answer by"Take me to Venice".

Answer 6

history major ... sorry