What does this error message mean?

Question

E:/ is not accessible.
The request could not be performed because of an I/O device error.

Answer 1

try this
going into hardware profiles for the CD Rom that wasn't reading, clicking on the advanced tab, and selecting "PIO only" instead of "DMA if Available" in win XP sp2

Answer 2

An error message is a message displayed when an unexpected condition occurs, usually on a computer or other device. Error messages are often displayed using dialog boxes. Error messages are used when user intervention is required, indicate that a desired operation has failed, or give very important warnings such as being out of hard disk space. Error messages are pervasive throughout computing, and are part of every operating system, software application, or computer hardware device. Proper design of error messages is an important topic in usability and other fields of human-computer interaction.

Here are some common computer-related error messages that occur in almost all programs and their causes:

"Out of memory" - occurs when you have run out of memory or load too big of a file to store in RAM. The fix is to close some programs or get more memory.
"You have run out of disk space" - occurs when the hard drive is full. When not enough memory is present, swap file is used and is stored on the hard drive. The fix is to close some programs (to free swap file usage) and delete some files, normally temporary files or get a bigger hard drive.
Invalid page fault errors
General protection fault errors
The blue screen of death
"File not found" - the file you were trying to open cannot be found. The file may have been damaged, moved, deleted, or a bug causes it
"The device is not ready" - most often occurs when you have no floppy disk in the floppy disk drive and try to perform tasks involving the floppy disk or from a bad disk

[edit] Famous Error Messages
Abort, Retry, Fail?
Windows 95 Windows has detected an undetectable error.
Bad command or file name

[edit] Error Message Linguistics
The amount of memory available to programs has historically increased exponentially according to Moore's Law; contrapositively, it decreases exponentially into the past.

Due to such pressures, past programmers were innately sensitive to memory consumption, and such sensitivities extended to error messages. Extraneous words were shunned, no matter their grammatical necessity. "File not found" could have read "The file could not be found," but such a statement would have been twice as memory-expensive.

Answer 3

Your optical drive (probably) doesn't have a CD or DVD in it.