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From what i know there's really nothing to be worried about. The positive & negatives in a blood group are called Rhesus factor and does not have any affect on the health of the child.

It happenned because of the combination of genes from you and your wife. The Rhesus system is much more complex than the ABO blood type system because there are more than 30 possible combinations.

Individuals either have, or do not have, the Rhesus factor (or Rh D antigen) on the surface of their red blood cells. This can be indicated with a plus (+) or minus (−) suffix after the ABO blood type (i.e. A- or O+).

When there is an incompatibility between the blood types of the mother and the baby (usually when the mother is negative but the baby in the womb is positive), a condition called Hemolytic Disease of the Newborn could occur (also called Erythroblastosis Fetalis).

What happens is that if some of the baby's blood from the first pregnancy gets into the mother's blood system, the mother would automatically produce antigens to combat it. This doesn't affect the first baby, but if the second baby is also positive, these antigens could come through the placenta and affect the second baby with Hemolytic Disease of the Newborn. However, modern day medicine has made it such that the vast majority of Rh disease is preventable in modern antenatal care by injections of IgG anti-D antibodies.

So there's really nothing to worry about... go have fun with your kids!

2007-01-18 00:09:10 · answer #1 · answered by maverick 2 · 0 0

Let us apply Mendel's law:
You are 0+, it means you are 00 ++ or +-
Your wife is A+, it means she is AA or A0, and ++ or +-
Let us analyse the 0's and A's first:
From the combinations you can have the children with the followings:
From the 00 and AA crosses: A0, A0, A0, A0. In this case your children must be 100% A0. Since A is dominant, all children will be A.
From the 00 and A0 crosses: A0, 00, A0, 00. So your children must be 50% A0 (and accordingly A since A is dominant), and 50% 0. If we combine both cases (00 cross AA and 00 cross A0) the probability is 2/8 or %25 that your child is an '0'.
Now let us analyse the +- cases:
From ++ cross ++ you will get ++,++,++,++ cases which means 100% +.
From +- cross ++ you will get ++, ++, +-, +- cases which means 100% + since '+' is dominant.
From ++ cross +- you will get ++, ++, +-, +- cases which means 100% + since '+' is dominant.
Finally from +- cross +- you will get ++, +-, +-,-- which means 75% + (since '+' is dominant) and 25%-.
So the probability to have a - child is 1/16 or %6.25.
To find the probability of the child with 0- we must combine the A's and 0's cases for 0 case (2/8 for '0') with the +'s and -'s case (1/16 for '-') . So the probability for you to have a baby with 0- under these conditions is 2/144 or 1/72 which means around 1.39%. If you have 139 children, one of them can be a '0-' according to Mendel's law. If you can knwo whether you are a 00 ++ or +- , and your wife is a AA or A0, and ++ or +-, you can get a more correct result of the calculation. From the information you are given the probability is low.
For more information about Menderl and his law you can use the following link:
http://en.wikipedia.org/wiki/Gregor_Mendel

2007-01-17 22:24:17 · answer #2 · answered by Refik N 1 · 0 0

Yes. Its okay. The blood group of the offspring does not have to be that of either of the parents.
Remember these tables:

Parents Children
Positive and positive Positive or negative
Positive and negative Positive or negative
Negative and negative Negative


Parents Possible children
O and O O
O and A O or A
O and B O or B
O and AB A or B
A and A O or A
A and B O or A or B or AB
A and AB A or B or AB
B and B O or B
B and AB A or B or AB
AB and AB A or B or AB

Yours is case 1in table 1 and case 2 in table 2, so the child can be either O or A positive or negative, which is confirmed by what you said. Don't worry. It's okay.

2007-01-17 21:54:18 · answer #3 · answered by Parry 3 · 0 0

The + or - sign after the group is the Rhesus factor. To my knowledge, it doesn't have to be the same as that of the parent who transmitted the Group (which is the capital letter), unless I'm strongly mistaken.

2007-01-17 21:42:22 · answer #4 · answered by Anonymous · 0 0

Yes, it's ok! Your wife has a hidden allele for the blood type O. This is her genotype: AO (but A is dominant, so her blood type is A).

2007-01-17 21:39:39 · answer #5 · answered by Barbara V 4 · 0 0

See the following to explain the Rh factor (ie. + and -). It is OK that your child is O-, and it is OK that this is a possible outcome of a child produced by you and your wife.

http://www.biology.arizona.edu/human_bio/problem_sets/blood_types/rh_factor.html

2007-01-17 22:09:28 · answer #6 · answered by teachbio 5 · 0 0

yaw its ok,and ur wife is +ve,it will be any blood group nothing to worry.if she is -ve,it willbe problem if the 2nd baby is -ve.
but here its not,ok then be cool,bye.

2007-01-17 23:22:07 · answer #7 · answered by siri 1 · 0 0

Yes, thats fine. Your childrens phenotypes are consistent with yours and your wife's. Your genotype should be OO+-, your wife's should be AO+-. Your childrens' genotypes are probably OO+- (or OO++) and OO--.

2007-01-18 04:30:46 · answer #8 · answered by Dr. Zaius 4 · 0 0

yes

2007-01-18 03:30:58 · answer #9 · answered by ♥♪♫Priya_akki™♫♪♥ 6 · 0 0

its k it is to be doubted only if the group itself changed not the rhesus type it can be any thing +ve or -ve

for example

+ve + +ve= +ve or -ve
+ve + -ve= +ve or -ve
-ve +-ve= -ve

2007-01-17 23:31:01 · answer #10 · answered by prassanthini r 1 · 0 0

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